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INDICATIONS AND USAGE

SPRYCEL® (dasatinib) is a prescription medicine used to treat:

  • adults with newly diagnosed Philadelphia chromosome–positive (Ph+) chronic myeloid leukemia (CML) in chronic phase
  • adults with Ph+ CML who no longer benefit from, or did not tolerate, other treatment, including imatinib
  • adults with Ph+ acute lymphoblastic leukemia (Ph+ ALL) who no longer benefit from, or did not tolerate, other treatment
  • children 1 year of age and older with Ph+ CML in chronic phase
  • children 1 year of age and older with newly diagnosed Ph+ ALL in combination with chemotherapy

It is not known if SPRYCEL is safe and effective in children under 1 year of age.

SPRYCEL for Ph+ CML in Children

How is SPRYCEL® (dasatinib) used to treat children with Ph+ CML in chronic phase (CP)?

If your child has been diagnosed with Philadelphia–positive (Ph+) chronic myeloid leukemia (CML), you may have questions. Here, you will find details about Ph+ CML in children and its treatment with SPRYCEL.

Find out more about SPRYCEL treatment in children with Ph+ CML in CP, including:

What are some important facts about Ph+ CML in children?

  • Ph+ CML is a form of leukemia, or cancer of the blood, that can affect children
  • CML is a chronic form of leukemia, meaning it is “slower growing” than other leukemias
  • Out of all the childhood leukemias, CML accounts for less than 3% of the total number of cases

Did you know?

Researchers discovered that the cause of Ph+ CML is connected to the Philadelphia chromosome. This is an abnormal chromosome that contains the BCR-ABL gene, which can lead to the overproduction of white blood cells. These white blood cells are often damaged and can crowd out healthy blood cells. This chromosome is found in almost everyone who has CML.

What is SPRYCEL?

SPRYCEL is a prescription medication used to treat children 1 year of age and older with Ph+ CML in chronic phase.

It is not known if SPRYCEL is safe and effective in children under 1 year of age.

What can we expect from treatment?

Your child’s doctor will discuss the treatment goals with you. He or she will see your child for follow-up appointments to check if your child is reaching those goals. The doctor will let you know how often your child should come for appointments and what tests to expect.

Quick tip: Keep all of your child’s doctor appointments to make sure he or she is on track.

BECOME AN INSPIRATION

“All of my doctors talked about milestones. We ended up talking about me getting to a specific number. And once I hit that number, we could go lower, but if I stayed there, that was perfectly fine.”
– Tiffany, SPRYCEL patient

WATCH TIFFANY’S STORY
Tiffany, a SPRYCEL® (dasatinib) patient
Tiffany, a SPRYCEL® (dasatinib) patient
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